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In the early steps of the anthocyanin pathway, chalcone isomerase-like proteins modulate the product specificity of chalcone synthase through proteinprotein interactions 35

84 Fluids from the disc draining into the bone marrow likely carry cytokines, chemokines, MMPs and MMP-cleaved matrix catabolites and trigger pro-fibrotic marrow changes and an inflammatory dysmyelopoiesis (Fig

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